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Lymphodepleting chemotherapy in order to safely improve the expansion of HER2-CAR T cells in patients with advanced sarcomas
⏲ 2 min 31 sec ✓ 09-Apr-2019
Donnie's Story
⏲ 1 min 32 sec ✓ 09-Aug-2021
Mosunetuzumab induces complete remissions in poor prognosis non-Hodgkin lymphoma patients
⏲ 2 min 89 sec ✓ 07-Dec-2019
Non Compos Bent This
⏲ 72 sec ✓ 07-Aug-2010
Expert Panel Discusses CAR T-Cell Therapy in Multiple Myeloma
⏲ 5 min 98 sec ✓ 12-Jan-2018
Phase II data from the KarMMa trial for relapsed refractory multiple myeloma
⏲ 3 min 52 sec ✓ 11-Jun-2020
Mosunetuzumab induces deep and durable remissions in 3L R R follicular lymphoma
⏲ 2 min 85 sec ✓ 11-Dec-2021
BELONGING IN THREE ACTS
⏲ 2 min 45 sec ✓ 20-Feb-2020
Anti-BCMA CAR T cell therapy for multiple myeloma
⏲ 6 min 87 sec ✓ 19-Dec-2017
Safety and efficacy of CD19 CD22 CAR T cells in children and young adults with relapsed refractory ALL
⏲ 3 min 70 sec ✓ 29-Jun-2020
Analyzing the Use of CAR-T Therapy for the Treatment of Multiple Myeloma
⏲ 2 min 54 sec ✓ 06-Dec-2020
ASH 2022: Multiple myeloma roundup
⏲ 16 min 85 sec ✓ 22-Dec-2022
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_lymphodepleting-chemotherapy-in-order-to-safely-improve-the-expansion-of-her2-car-t-cells-in-patients-with-advanced-sarc.webp "Prof Shoba Navai speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about results from a study looking at lymphodepleting chemotherapy in order to safely improve the expansion of HER2-CAR T cells in patients with advanced sarcomas.nnShe explains that the study succeeded in safely doing this with very limited toxicities seen and no cardiac toxicities which can be seen in other HER-2 directed therapies.nnProf Navai reports that the addition of lymphodepletion did")
_donnie39s-story.webp "Cancer is a disease that affects millions of people world wide. When Donato Bernardo was told that he had cancer, he knew he wasn’t going to stop at anything to fight it. He began a 5 year battle that would see him undergoing every known treatment in the system. Despite experiencing some mild success at first, the cancer was relentless, and he was out of conventional treatment options. It was at this point that he was approached about participating in a clinical trial.nnA study using Chimeric")
_mosunetuzumab-induces-complete-remissions-in-poor-prognosis-non-hodgkin-lymphoma-patients.webp "Prof Stephen Schuster speaks to ecancer at the 2019 ASH meeting in Orlando about the use of mosunetuzumab in patients with non-Hodgkin lymphoma. nnHe describes the design of this study, along with the results achieved and toxicities observed with the action of this dual-targeting antibody. nnProf Schuster elaborates on this unmet need for patients who do not respond to CAR T-cell therapy. nnHe concludes by discussing the future use of this drug which is easily accessible due to its")
_non-compos-bent-this.webp "An installation based on Hear Motion Synesthesia. nnSynesthesia is a benign neurological condition in humans characterized by involuntary cross-activation of the senses, and estimated to affect at least 1% of the population. Multiple forms of synesthesia exist, including distinct visual, tactile or gustatory perceptions which are automatically triggered by a stimulus with different sensory properties such as seeing colors when hearing music.nNew discoveries have led scientists to the discovery o")
_expert-panel-discusses-car-t-cell-therapy-in-multiple-myeloma.webp "World Myeloma Forum Expert Panel members Sagar Lonial, MD; Suzanne Lentzsch, MD, PhD; Ravi Vij, MD, MBA; and Ola Landgren, MD, PhD discuss data presented at ASH 2017 on the use of CAR T-Cell Therapy in Multiple Myeloma.nnThe panel discusses three abstracts presented at ASH using CAR T-Cell Therapy and their implication in the management of patients with Multiple Myeloma:nnAbstract 505: Safety and Efficacy of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA)")
_phase-ii-data-from-the-karmma-trial-for-relapsed-refractory-multiple-myeloma.webp "Prof Nikhil Munshi talks to ecancer in an online interview for the ASCO virtual meeting 2020 about the KarMMa study. nnThe KarMMa study looks at CAR T-cell therapy with BCMA-targeting idecabtagene-vicleucel (ide-cel).nnIt resulted in deep and durable responses in heavily pretreated patients with relapsed/refractory multiple myeloma.nnDr Munshi provides a detailed account of the trial design, results, and toxicity profile.nnSign up to ecancer for free to receive tailored email alerts for more vid")
_mosunetuzumab-induces-deep-and-durable-remissions-in-3l-r-r-follicular-lymphoma.webp "Prof Elizabeth Budde speaks to ecancer about the pivotal results from a phase I/II Study investigating mosunetuzumab monotherapy as an effective and well-tolerated treatment option for patients with relapsed/refractory (R/R) follicular lymphoma (FL) who have received ≥2 prior lines of therapy. Initially, she talks about the background of the study. Prof Budde says that the primary endpoint was complete response rate by PET/CT assessed by an independent review facility (IRF) using standard resp")
_belonging-in-three-acts.webp "on the assemblage of unspoken thoughts is an on-going")
_anti-bcma-car-t-cell-therapy-for-multiple-myeloma.webp "Dr Kochenderfer presents, in a press conference at the 2017 ASH annual meeting, updated results from a multicenter study of bb2121 anti-BCMA CAR T cell therapy.nnRead the news story or watch the interview with Dr Kochenderfer for more.")
_safety-and-efficacy-of-cd19-cd22-car-t-cells-in-children-and-young-adults-with-relapsed-refractory-all.webp "Dr Haneen Shalabi speaks to ecancer in an online interview for the virtual AACR 2020 meeting. nnShe discusses the results of the phase 1 dose-escalation study evaluating the safety and efficacy of CD19/CD22 CAR T cells in children and young adults with relapsed/refractory ALL.nnDr Shalabi goes through the background to the study and talks us through the methodology used.nnShe reports that the CAR T cells were well tolerated at all dose levels with a reversible side effect profile and patients di")
_analyzing-the-use-of-car-t-therapy-for-the-treatment-of-multiple-myeloma.webp "Deepu Madduri, MD, assistant professor, Hematology and Medical Oncology of the Mount Sinai Hospital, Mount Sinai Beth Israel, discusses the results of the CARTITUDE-1 study, which analyzed ciltacabtagene autoleucel, a CAR-T-cell therapy with 2 B-cell maturation antigen–targeting single-domain antibodies, for the treatment of patients with relapsed/refractory multiple myeloma.")
_ash-2022-multiple-myeloma-roundup.webp "Dr Tom Martin speaks to ecancer about the key data presented at the ASH 2022 conference.nnHe starts off by updating us on the Ikema subgroup analysis investigating isatuximab plus carfilzomib and dexamethasone in patients with early versus late relapsed multiple myeloma.nnThe study showed that the addition of Isa to Kd improved PFS and depth of response, with a manageable safety profile in both early and late relapse patients, consistent with the benefit observed in the overall IKEMA study pop")
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